It was found that the magnitude of the vasodilatation induced by severe hypoxia was unaffected by the addition of L-NA and indomethacin, demonstrating that it was not due to an involvement of the endothelial factors nitric oxide (NO) and/or prostaglandins

It was found that the magnitude of the vasodilatation induced by severe hypoxia was unaffected by the addition of L-NA and indomethacin, demonstrating that it was not due to an involvement of the endothelial factors nitric oxide (NO) and/or prostaglandins. & Collins, 1994 (rabbit coronary)). However, in some studies, the responses have been found to […]

Oncogenic mutations in BRAF lead to regulation-uncoupled phosphorylation events (1, 5, 45)

Oncogenic mutations in BRAF lead to regulation-uncoupled phosphorylation events (1, 5, 45). is the intramolecular binding of autoinhibitory modules (Goal) to practical protein domains, which can be of a different kind (36). Conformational transitions are initiated by binding events, different means of post-translational modifications (PTM), or Goal proteolysis. Besides binary complex formation of autoinhibitory proteins […]